IGF-1 LR3

IGF-1 LR3 is a modified, long-acting analog of insulin-like growth factor 1 (IGF-1), a downstream mediator of growth hormone's effects on tissue. The molecule has been engineered with an amino acid substitution that reduces its binding to IGF-binding proteins, extending its half-life and biological activity compared to native IGF-1. IGF-1 binds to IGF-1 receptors found on muscle, cartilage, and connective tissue, activating intracellular signaling cascades (including the PI3K/Akt/mTOR pathway) involved in protein synthesis and cellular growth and repair processes. As a prescription-only peptide, EdgeRx makes IGF-1 LR3 available exclusively through a clinician-supervised protocol, prescribed by licensed physicians for eligible patients based on individualized clinical assessment.